Position #173 – Chemical Biology Lab.

Host institution
JP - Okayama University (岡山大学)
Lab or research department name
Graduate School of Natural Science and Technology
Domain
Chemical Engineering
Type of mobility
doctoral
Duration (months)
From 6 months
Description

Our major concern is to develop RNA technologies and peptide technologies, and to expand protein biosynthesizing system to incorporate synthetic analogs of existing biomolecules.

Design of RNA carrier molecule and development of RNA delivery method.
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Bioconjug. Chem. 22, 2222–2226 (2011)
J.Biosci.Bioeng., 109, 189–192 (2010)
Bioorg.Med.Chem.Lett. 19, 3410–3413 (2009)

CLIP-RNAi technology (Spatial regulation of RNA interference by light).
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J.Control.Release, 137, 241–245 (2009)
Bioconjug.Chem. 19, 1017–24 (2008)

Expansion of protein biosynthesis system, and its application.
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Anal. Biochem., 418, 97–101 (2011)
Biochem. Biophys. Res. Commun. 414, 625–630 (2011)
J. Biochem , 148, 239–246 (2010)
Anal Biochem. 390, 121–125 (2009)
J. Am. Chem. Soc. 129, 14458–62 (2007)
Anal Biochem. 348, 321–3 (2006)
FEBS lett. 579, 6769–6774 (2005)
Nat.Biotech. 20, 177–182 (2002)

Mitochondrial translation system (especially, about tRNAs and elongation factors with unusual structures)
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IUBMB life, 59, 68–75 (2007)
Nucleic Acids Res. 34, 5291–9 (2006)
Biochemical J., 399, 249–256 (2006)
Biochemistry, 45, 10920–10927 (2006)
Nucleic Acids Res. 33, 4683–4691 (2005)
Biochemistry, 44, 9232–9237 (2005)
FEBS lett. 579, 2767–2772 (2005)
Nucleic Acids Res. 33, 1653–1661 (2005)
Nucleic Acids Res. 30, 5444–5451 (2002)
Nat.Struct.Biol. 9, 669–673 (2002)
J.Biol.Chem. 276, 21571–21577 (2001)

Development of the methods for RNA isolation and RNA detection using artificial nucleic acids.
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J. Biochem. 144, 415–8 (2008)
Chem.Lett. 38, 438–439 (2009)

When
From January 2016
Maximum available positions
1
Prerequisites
Doctoral candidates are invited to propose a research topic and select a host, which are related to their proposed doctoral research. For inquiries and laboratory introductions please contact the address below.
Contact
Pr. T. Ohtsuki <ohtsuk@cc.okayama-u.ac.jp>
URL
http://www.biotech.okayama-u.ac.jp/labs/ohtsuki/field8-e.html